Game Details:
Matchup: Eagles vs Chargers
Date & Time: Sunday, December 7, 2025 | 8:20 PM ET
Venue: SoFi Stadium, Inglewood, CA
Betting Line: Chargers -2.5 | Over/Under: 46.0
Key Storylines
Playoff Implications on the Line
With December football in full swing, both the Eagles and the Chargers find themselves in the thick of playoff races in their respective conferences. The Chargers, currently holding onto a Wild Card spot in the AFC, are looking to defend home turf and solidify their postseason positioning. Meanwhile, the Eagles trail the division-leading Cowboys in the NFC East and cannot afford any more slip-ups.
Herbert vs Hurts — QB Duel to Watch
Both Justin Herbert and Jalen Hurts have had up-and-down seasons by their standards, but their dual-threat capabilities and arm talent will be on full display in this highly anticipated matchup. Hurts has accounted for over 25 total touchdowns this season, while Herbert has thrown for over 3,400 yards despite a depleted wide receiving corps.
Injury Report
Eagles:
Out: CB Darius Slay (knee), WR Quez Watkins (hamstring)
Questionable: OL Lane Johnson (ankle), RB Kenneth Gainwell (concussion)
Chargers:
Out: WR Mike Williams (ACL), LB Eric Kendricks (hamstring)
Questionable: RB Austin Ekeler (shoulder), DE Joey Bosa (toe)
Betting Trends
Against the Spread (ATS):
Eagles: 6-6 ATS this season
Chargers: 7-5 ATS this season
Over/Under Trends:
The total has gone over in 4 of the Eagles’ last 6 road games
The total has gone over in 7 of the Chargers’ last 9 games at home
Matchup Insight
The Eagles’ defense has struggled over the past month, especially in the secondary, allowing a league-worst 288 passing yards per game over the last four weeks. That could spell trouble against a vertical-heavy Chargers offense, even with Mike Williams sidelined. However, the Chargers also rank near the bottom in rushing defense, giving Jalen Hurts and D’Andre Swift a chance to control the game on the ground.
Player Prop to Watch
Keenan Allen (Chargers) – Receiving Yards Total: 84.5
Allen remains Herbert’s go-to target and should feast on a banged-up Eagles secondary. The over looks like solid value here if Allen gets his usual 10+ targets.
Jalen Hurts (Eagles) – Anytime Touchdown Scorer
Hurts has 10 rushing touchdowns this season and remains the centerpiece of Philly’s red zone offense.
Prediction & Best Bets
Spread: Eagles +2.5 → In a coin-flip game, the points carry value. Philadelphia’s ground game can keep this close if Hurts takes over.
Total: Over 46.0 → Both defenses are susceptible to big plays, and star quarterbacks are capable of lighting up the scoreboard.
Player Prop: Keenan Allen Over 84.5 receiving yards → Expect a high target share against a weak Eagles secondary.
This one shapes up to be a prime-time thriller. Both squads are hungry for critical wins, but a healthier roster and home-field edge could push the Chargers over the top in the final minutes.
Final Score Prediction: Chargers 27, Eagles 24