Game Details:
Matchup: Cardinals vs Cowboys
Date & Time: Monday, November 3, 2025 | 8:15 PM ET
Venue: AT&T Stadium – Arlington, TX
Betting Line: Cowboys -9.5 | Over/Under: 45.5
Key Storylines
Cowboys Riding High at Home
Dallas has once again established itself as a home-field powerhouse, entering Week 9 with a 4-0 record at AT&T Stadium and winning those games by an average of 17.2 points. With quarterback Dak Prescott playing turnover-free football and the defense among the league’s best, the Cowboys are looking to continue their dominance in prime time against a reeling Cardinals squad.
Cardinals Facing Offensive Struggles
Arizona enters Monday night in transition, with first-year head coach and a banged-up roster. The quarterback situation remains in flux with Kyler Murray still not expected to return from knee surgery and backup options struggling to generate consistent offense. The Cardinals have scored fewer than 17 points in four of their last five games, making them heavy underdogs in Arlington.
Cowboys’ Defense Could Feast
Dallas currently ranks top 3 in total defense and leads the league in turnover differential (+11). Their pass rush, led by Micah Parsons, will look to torment Arizona’s patchwork offensive line. The Cardinals have allowed the fourth-most sacks this season, a troubling stat heading into this matchup.
Injury Report
Cardinals:
Out: Kyler Murray (knee), James Conner (knee), Budda Baker (hamstring)
Questionable: Marquise Brown (groin), Jalen Thompson (calf)
Cowboys:
Out: Leighton Vander Esch (neck), Tyron Smith (knee)
Questionable: Rico Dowdle (ankle)
Betting Trends
- Against the Spread (ATS):
Cardinals: 2-5 ATS this season
Cowboys: 5-2 ATS this season - Over/Under Trends:
The total has gone under in 5 of Arizona’s 7 games
The total has gone under in 4 of Dallas’ last 6 home games - Head-to-Head:
Cardinals have won 3 of the last 4 meetings—but Dallas covered in 2 of those
Player Props to Watch
CeeDee Lamb (DAL): Receiving Yards Total – 77.5
Lamb has posted back-to-back 100-yard games and faces a Cardinals secondary missing key playmakers.
Micah Parsons (DAL): Sacks Prop – 1.0
With Arizona allowing heavy pressure, look for Parsons to add to his sack total. The over could be a smart play here.
Prediction & Best Bets
Spread: Cowboys -9.5 → Given Arizona’s offensive issues and Dallas’ home dominance, this line feels justified. Expect Dallas to control both tempo and the scoreboard.
Total: Under 45.5 → With Arizona struggling to score and Dallas likely content to run down the clock with a big lead, this could be a lower-scoring affair.
Player Prop: CeeDee Lamb Over 77.5 Receiving Yards → Lamb has emerged as Prescott’s go-to target, and Arizona’s defense hasn’t proven it can contain elite wideouts.
Final Score Prediction: Cowboys 27, Cardinals 13